Развитие биопленки и определение кворума (QS) — тесно взаимосвязанные процессы. Биопленка относится к сложным сидячим сообществам микробов, которые обнаруживаются либо прикрепленными к поверхности, либо прочно погруженными во внеклеточный матрикс в виде агрегатов. QS представляет собой механизм межклеточной коммуникации, который синхронизирует экспрессию генов в ответ на плотность клеток популяции. Наша цель — определить этапы формирования биопленки, роль системы кворум-сенсинга в ее создании и то, как система кворум-сенсинга устроена у грамотрицательных и положительных бактерий.
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