Antisytokin-anti-inflammatory treatments, coagulopathy management

Abstract

There is no evidence that anti-cytokine therapies are effective in the treatment of CRDS, which has a history of 53 years, and sepsis, and these drugs are not used in routine treatment. Protective mechanical ventilation of the lungs is the only method used in the treatment of CRDS that has been shown to increase survival through randomized controlled trials. Sepsis is generally considered to be an immunosuppressive condition, and the most common causes of death are nosocomial and opportunistic infections. There is evidence that treatments such as the monoclonal tocilizumab antibody, which has an anti-IL6R effect, may themselves cause CRDS.