Newborns are at high risk due to immaturity of the immune system, the possibility of vertical transition at birth without evidence, the possibility of perinatal contact through urine and feces during vaginal birth, and close postpartum contact with an asymptomatic infected mother. Therefore, an appropriate approach to suspicious and specific cases in the perinatal and neonatal period should be taken in collaboration with the relevant departments.
The main route of infection is by droplets and contact, with an average incubation period of 3-7 days (min-max: 1-14 days). There are also studies showing fecal-oral transmission. The cynical form is not pathognomonic: changes in vital signs (thermolability, tachypnoea, tachycardia), difficulty breathing (wheezing, nasal congestion, apnea, cough), gastrointestinal symptoms (vomiting, diarrhea, abdominal distension) and lethargy may be observed.
Zhu H, Wang L, Fang C, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr 2020;9(1):51-60.
Wang L, Shi Y, Xiao T, et al. Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (First edition). Ann Transl Med 2020;8(3):47.
Chen Y, Peng H, Wang L, et al. Infants Born to Mothers With a New Coronavirus (COVID-19). Front Pediatr 16 March 2020.
Wang J, Qi H, Bao L, et al. A contingency plan for the management of the 2019 novel coronavirus outbreak in neonatal intensive care units. Lancet Child Adolesc Health 2020;4(4): 258-259.
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